![Frontiers | Platycodin D induces apoptosis through JNK1/AP-1/PUMA pathway in non-small cell lung cancer cells: A new mechanism for an old compound Frontiers | Platycodin D induces apoptosis through JNK1/AP-1/PUMA pathway in non-small cell lung cancer cells: A new mechanism for an old compound](https://www.frontiersin.org/files/Articles/1045375/fphar-13-1045375-HTML/image_m/fphar-13-1045375-g007.jpg)
Frontiers | Platycodin D induces apoptosis through JNK1/AP-1/PUMA pathway in non-small cell lung cancer cells: A new mechanism for an old compound
![Inhibiting aberrant p53-PUMA feedback loop activation attenuates ischaemia reperfusion-induced neuroapoptosis and neuroinflammation in rats by downregulating caspase 3 and the NF-κB cytokine pathway | Journal of Neuroinflammation | Full Text Inhibiting aberrant p53-PUMA feedback loop activation attenuates ischaemia reperfusion-induced neuroapoptosis and neuroinflammation in rats by downregulating caspase 3 and the NF-κB cytokine pathway | Journal of Neuroinflammation | Full Text](https://media.springernature.com/lw685/springer-static/image/art%3A10.1186%2Fs12974-018-1271-9/MediaObjects/12974_2018_1271_Fig4_HTML.png)
Inhibiting aberrant p53-PUMA feedback loop activation attenuates ischaemia reperfusion-induced neuroapoptosis and neuroinflammation in rats by downregulating caspase 3 and the NF-κB cytokine pathway | Journal of Neuroinflammation | Full Text
![The role of P53 up-regulated modulator of apoptosis (PUMA) in ovarian development, cardiovascular and neurodegenerative diseases | SpringerLink The role of P53 up-regulated modulator of apoptosis (PUMA) in ovarian development, cardiovascular and neurodegenerative diseases | SpringerLink](https://media.springernature.com/lw685/springer-static/image/art%3A10.1007%2Fs10495-021-01667-z/MediaObjects/10495_2021_1667_Fig1_HTML.png)
The role of P53 up-regulated modulator of apoptosis (PUMA) in ovarian development, cardiovascular and neurodegenerative diseases | SpringerLink
![PUMA gene and protein structure. The human PUMA gene contains three... | Download Scientific Diagram PUMA gene and protein structure. The human PUMA gene contains three... | Download Scientific Diagram](https://www.researchgate.net/publication/26704262/figure/fig2/AS:281230605078530@1444062009141/PUMA-gene-and-protein-structure-The-human-PUMA-gene-contains-three-coding-exons-exons.png)
PUMA gene and protein structure. The human PUMA gene contains three... | Download Scientific Diagram
![The role of P53 up-regulated modulator of apoptosis (PUMA) in ovarian development, cardiovascular and neurodegenerative diseases | SpringerLink The role of P53 up-regulated modulator of apoptosis (PUMA) in ovarian development, cardiovascular and neurodegenerative diseases | SpringerLink](https://media.springernature.com/lw685/springer-static/image/art%3A10.1007%2Fs10495-021-01667-z/MediaObjects/10495_2021_1667_Fig2_HTML.png)
The role of P53 up-regulated modulator of apoptosis (PUMA) in ovarian development, cardiovascular and neurodegenerative diseases | SpringerLink
![A review of the role of Puma, Noxa and Bim in the tumorigenesis, therapy and drug resistance of chronic lymphocytic leukemia | Cancer Gene Therapy A review of the role of Puma, Noxa and Bim in the tumorigenesis, therapy and drug resistance of chronic lymphocytic leukemia | Cancer Gene Therapy](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fcgt.2012.84/MediaObjects/41417_2013_Article_BFcgt201284_Fig1_HTML.jpg)
A review of the role of Puma, Noxa and Bim in the tumorigenesis, therapy and drug resistance of chronic lymphocytic leukemia | Cancer Gene Therapy
![The role of P53 up-regulated modulator of apoptosis (PUMA) in ovarian development, cardiovascular and neurodegenerative diseases | SpringerLink The role of P53 up-regulated modulator of apoptosis (PUMA) in ovarian development, cardiovascular and neurodegenerative diseases | SpringerLink](https://media.springernature.com/lw685/springer-static/image/art%3A10.1007%2Fs10495-021-01667-z/MediaObjects/10495_2021_1667_Fig3_HTML.png)
The role of P53 up-regulated modulator of apoptosis (PUMA) in ovarian development, cardiovascular and neurodegenerative diseases | SpringerLink
![Schematic diagram of p53 and PUMA regulation of apoptosis following... | Download Scientific Diagram Schematic diagram of p53 and PUMA regulation of apoptosis following... | Download Scientific Diagram](https://www.researchgate.net/publication/224910068/figure/fig11/AS:667076452683790@1536054828431/Schematic-diagram-of-p53-and-PUMA-regulation-of-apoptosis-following-cisplatin-treatment.png)
Schematic diagram of p53 and PUMA regulation of apoptosis following... | Download Scientific Diagram
![The pro-apoptotic protein Bmf co-operates with Bim and Puma in neuron death induced by β-amyloid or NGF deprivation - ScienceDirect The pro-apoptotic protein Bmf co-operates with Bim and Puma in neuron death induced by β-amyloid or NGF deprivation - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S1044743117303706-fx1.jpg)
The pro-apoptotic protein Bmf co-operates with Bim and Puma in neuron death induced by β-amyloid or NGF deprivation - ScienceDirect
![WRN suppresses p53/PUMA-induced apoptosis in colorectal cancer with microsatellite instability/mismatch repair deficiency | PNAS WRN suppresses p53/PUMA-induced apoptosis in colorectal cancer with microsatellite instability/mismatch repair deficiency | PNAS](https://www.pnas.org/cms/10.1073/pnas.2219963120/asset/379249bb-a5ef-437c-950f-999085227123/assets/images/large/pnas.2219963120fig01.jpg)
WRN suppresses p53/PUMA-induced apoptosis in colorectal cancer with microsatellite instability/mismatch repair deficiency | PNAS
BH3-only sensors Bad, Noxa and Puma are Key Regulators of Tacaribe virus-induced Apoptosis | PLOS Pathogens
![Phosphorylation of Puma modulates its apoptotic function by regulating protein stability | Cell Death & Disease Phosphorylation of Puma modulates its apoptotic function by regulating protein stability | Cell Death & Disease](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fcddis.2010.38/MediaObjects/41419_2010_Article_BFcddis201038_Fig1_HTML.jpg)
Phosphorylation of Puma modulates its apoptotic function by regulating protein stability | Cell Death & Disease
![ART increases PUMA protein level. PANC-1 (A), BxPC-3 (B), and HCT116... | Download Scientific Diagram ART increases PUMA protein level. PANC-1 (A), BxPC-3 (B), and HCT116... | Download Scientific Diagram](https://www.researchgate.net/publication/321702205/figure/fig5/AS:569629856759813@1512821749535/ART-increases-PUMA-protein-level-PANC-1-A-BxPC-3-B-and-HCT116-C-cells-were.png)